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The Metabolic Laboratory is located in the Translational Research Institute for Metabolism and Diabetes (TRI), a partnership between Florida Hospital and Sanford-Burnham Medical Research Institute. It was completed in 2012. It was the first laboratory two operate “flex” rooms that can be converted between a configuration suitable for measuring the effects of drugs or nutrients on energy and fat metabolism during rest (about 3 m3) and a configuration for careful tests of exercises and physical activities (5 m3). The other two calorimeters are large units, about the size of a college dorm room, and are intended for maximum comfort during studies that can last several days.