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The 20 m3 calorimeter is located in the Clinical Research Unit at Vanderbilt University Medical Center (VUMC). In 2010 MEI worked with VUMC to replace the gas sample preparation and instrumentation package and software; guided alterations to the chamber; and built a gas blender for calibration and infusion simulations. Since that original effort we have continued scientific collaboration (including presentations at 3 conferences) and through a support contract. In 2012 VUMC received the first installation of CalRQ™ v2.5 Calorimeter Control Software.